nuri77The mechanism of Nur77 regulating cell survival and apoptosis in CNS. Nur77 mediates cell apoptosis through caspase, endoplasmic reticulum stress, and mitochondrial autophagy, whileNur77 responds to a wide range of physiological molecules and stimuli. 4, 14 These snals quickly induce Nur77 expression and stimulate its transcriptional activity; Nur77